Biology 101

Running Head : GENES AND THE ENVIRONMENTOn the Interaction of Genes and Environment in reaping pincer jail carrellular telephoneular phone AnemiaOn the Interaction of Genes and Environment in reaping trammel Cell AnemiaSickle mobile phone anaemia is a factortic blood dis which come acrosss haemoglobin the protein carried by red blood cells and creditworthy for carrying oxygen end-to-end the body (robin , 2007 . The inheritance pattern for the dis is autosomal recessive allele in that the mortal needs to be homozygous for the reap hook cell allele in for it to manifest (Krogh , 2005Sickle cell anemia affects passel globally although it occurs more frequently in people of explicit ethnicities . For instance , 70 000 to 80 000 Americans as note to two million people of African descent (Robin , 2007 ) are affect by the infirmityAlthough the frequency of reaping hook cell trait in Africa was thrice as much to that in America the disorder itself was much less common . Various hypotheses have been proposed in to account for this discrepancy such as better wellness of the adult African population higher African sis mortality rate as well as take a crap hold healthy conceptions in the United States . A determination during the aboriginal 1950s however has led to the definitive causation prat the difference : the huge impact of the purlieu on genes in sickle cell anemiaAnthony Allison , driven by the results build by E . A . Beet in labor union Rhodesia in 1946 , studied the interaction between sickle cell anemia and malaria . He found that the frequency distribution of the sickle cell condition mapped very closely to that of the most unrelenting forms of malaria (Natural Sciences learning Center , 2003 . Using the concept of balanced pleomorphism , he explained the results he ach ieved . He reasoned out that heterozygous in! dividuals for haemoglobin S had better chances of combating the effects of malaria over those who had practice hemoglobin As such , the deleterious effect of homozygosity in the recessive gene is offset and the high prevalence of the recessive gene in the population is maintainedIt is thus constructive to no(prenominal) that not all mutations are disadvantages .

In most cases , the environment compensates and makes them plus and necessaryReferencesKrogh , David (2005 . Biology : A Guide to the Natural terra firma , tertiary Edition . New Jersey : Prentice - foyer , IncMiller , Robin (2007 . Sickle CellAnemia . Nemours Foundation localise Retrieved declination 15 , 2007 , from HYPERLINK hypertext transfer protocol /network .kidshealth .org /teen /diseases_conditions /genetic /sickle_cell_ anemia .html http /www .kidshealth .org /teen /diseases_conditions /genetic /sickle_cell_a nemia .htmlNatural Sciences Learning Center (2003 . Biogeography and ecology of Sickle Cell Anemia . Washington University - Biology Site . Retrieved December 15 , 2007 from HYPERLINK http /www .nslc .wustl .edu /sicklecell /part3 /biogeography .html http /www .nslc .wustl .edu /sicklecell /part3 /biogeography .html deviate sickle shaped red blood cells , as contrast to their approach pattern disc -shaped appearance is the physical manifestation of the dis and results to the cells d which is responsible for carrying oxygen throughout the body . It is recessive in that the person needs to be homozygous for the sickle cell allele for the dis...If you want to get a full essay, localize it on our website: OrderCustomPaper.com

If you want to get a full essay, visit our page: write my paper